DELETED: Stability of PharmaceuticalsLaajuus (3.5 cr)
Course unit code: C-10088-4217548
General information
- Credits
- 3.5 cr
- Teaching language
- English
- Finnish
- Institution
- University of Eastern Finland
Objective
Learning outcomes: Stability is an essential quality parameter of pharmaceuticals. The aim of the course is to teach theory behind the drug stability which all pharmacists should know. After the course: - You know the main degradation mechanisms of the drugs and the how pH, temperature and other factors are affecting on drug stability. - You are familiar with the methods which can be used to improve the drug stability. - You can perform the stability study and you know which essential parameters you have to think before the study - You can calculate stability parameters from the laboratory data and you know how to perform stability studies at elevated temperatures. - You are familiar with the regulatory aspects dealing with the drug stability.
Content
The course deals with the chemical, physical and microbiological stability of pharmaceuticals including the regulatory aspects. The course describes the mathematical models of degradation kinetics and it contains also the laboratory work.
Materials
Lecture materials
Further information
Teachers: Senior lecturer Pekka Jarho Time: Spring semester Offering data: PR4, PR5, graduate students Key words: Stability of pharmaceuticals, hydrolysis, oxidation, physical stability Campus: Kuopio campus, School of Pharmacy Further information: Pekka Jarho, pekka.jarho(at)uef.f Office hilkka.wessman(at)uef.fi Teaching language: English/Finnish (if all the students are speaking finnish) Course includes elements of sustainable development (i.e., environmental protection, management of natural resources, health)
Execution methods
Lectures 18 h, tutorial 6 h, independent study 60 h, calculation practicals 2 h
Accomplishment methods
Modes of study: Final exam, practical exercises Evaluation criteria: The grade of the course is dependent on exam (80%) and laboratory exercise (20%). The maximum amount of points is 100 and to pass the course the student should get at least 50 points from the exam and laboratory exercise.